The first episode features Mark Gagliardi recounting the story of Alexander Hamilton’s famous duel with Aaron Burr after drinking a bottle of Scotch. Though it is unclear how large the bottle was, it was clearly quite a bit of liquor, as he spends most of his segment reclined on a couch with a bucket nearby, just in case. Hamilton is played by a suitably innocent-looking Michael Cera in the reenactment, but the real show-stealer is Jake Johnson in a brilliantly shifty-eyed performance as the loathsome Aaron Burr. In episode 2, Eric Falconer takes on the famous story of Benjamin Franklin‘s discovery of electricity, expounding upon his theory that it was actually Franklin’s “bastard son,” William (Clark Duke), who actually flew the legendary kite with the key tied to it. This is also the series’ first instance of vomiting in the midst of the storytelling, but not its last, so be warned that the series is not for the weak-stomached. Jack Black portrays Franklin again in a special volume 2.5 episode, in which Falconer tells a hilarious tale of Franklin’s sexual deviance.

Episode 3 features Jen Kirkman‘s account of Oney Judge (Tymberlee Hill), a female slave of George Washington (Danny McBride) that is especially funny because of the way the actors incorporate Kirkman’s frequent hiccups into their performances. The fourth episode features J.D. Ryznar‘s unwise decision to drink vodka and beer together, which obviously leads to more vomiting, and his account of the U.S. president William Henry Harrison (Paul Schneider), who died after only 32 days in office. Jen Kirkman returns for episode 5, in which Don Cheadle gives a hilarious performance as Frederick Douglass; there is something especially funny about Kirkman’s slurred words coming out of this revered actor’s mouth. Finally, in episode 6, Duncan Trussell follows six beers with a half-bottle of absinthe, and more vomiting ensues. He also tells the story of Nikola Tesla (John C. Reilly) and his contentious relationship with Thomas Edison (the always intensely weird Crispin Glover).

These are the only official episodes of the series (plus a very special Christmas episode included below), so beware of the unofficial knockoffs, most of which are pretty terrible. In fact, the one I linked to there is pretty much the only one that’s watchable, and it’s still nowhere near as good as the real thing. In addition to the recognizable stars, look for Waters’ name and also that of series director Jeremy Konner to avoid being duped.

Check out some of the other (non-exclusive) covers after the jump, along with HBO’s press release for Season 2 of “Eastbound & Down” and a couple of clips to further assist you in surviving ’til Sunday night.

Arrogant, washed-up big league pitcher Kenny Powers thought heʼd scored a shot at a comeback in the majors, but the offer turned out to be bogus. Now, having left his North Carolina life behind, heʼs making a fresh start in a small Mexican town, where he can both nurse his wounds and bless the locals with his awesomeness. “Eastbound & Down” kicks off its seven-episode second season Sunday, Sept. 26 (10:30-11:00 p.m. ET/PT), with other new episodes debuting subsequent Sundays at the same time.

Starring Danny McBride (“Up in the Air,” “Tropic Thunder”), “Eastbound & Down” tells the story of Kenny Powers, who used to be a star pitcher until his self destructive behavior knocked him out of Major League Baseball. In the first season of the series, he returned home to North Carolina to teach Phys Ed at the middle school he once attended, and eventually scored another big-league job offer – or so he imagined.

“Eastbound & Down” also stars Steve Little as Stevie Janowski, the high-school band teacher who idolizes Kenny; Michael Pena as Sebastian Cisneros, owner of the local Mexican baseball team; Ana de la Reguera as sultry lounge singer Vida; Marco Rodriguez as Roger Hernandez, manager of the baseball team; Efren Ramirez as his new neighbor Catuey; Elizabeth De Razzo as Maria, another new neighbor; Deep Roy as Aaron, one of Kennyʼs new sidekicks; and Joaquin Cosio as Hector, Kennyʼs other new sidekick.