The discomfort starts strong right out of the gate in the first episode, in which Galifianakis basically molests Michael Cera. There is a common thread of one-sided sexual tension in many of the episodes, and certainly not just with the female guests, though it may be strongest in the episode featuring Natalie Portman. It is a testament to her skill as an “acteress” that this episode is one of the most authentic, as if she were actually just in the midst of a nightmarish interview set up by the most incompetent agent imaginable. Other episodes are more clearly staged, and perhaps the weakest is the one with Will Ferrell, if only because the two are generally too chummy with each other, at least until the end.

The series is at its best when Galifianakis is openly hostile to his guests, like the episodes featuring Ben Stiller and “Brad Lee Cooper.” Though this hostility is common throughout the series, only “Conan O. Brien” gets an explanation, which is that Galifianakis thought he had a shot at “The Tonight Show.” Another especially convincing episode features Galifianakis’ “twin brother,” Seth, interviewing a wooden-faced Sean Penn, who really seems like he might haul off and punch Galifianakis at any moment. As with Portman, it is Penn’s acting skill that pulls off the joke so well.

A pitch-perfect spoof of bad, desperate public access talk shows, “Between Two Ferns” is easily one of the best offerings from the always enjoyable Funny or Die. Even the opening and closing theme music feels authentic, though it is actually lifted from Bernard Herrmann‘s “Taxi Driver” score, which adds to Galifianakis’ creepy, angry vibe. I’m not sure how well it would work as a full-length show on television, but in the small segments available online, it is hilarious.